Immunology

课程简介

/ Indicative Syllabus Components of the Immune system Barriers, bactericidal components in various body fluids and cells of the innate and adaptive immune systems; soluble mediators of immunity including the complement system and cytokines; the lymphoid system. Activation of the immune system Concept of clonal selection; activation and expansion of the B-cells and T cells; concept of MHC restriction and TCR recognition; exogenous and endogenous antigen processing; the antibody responses. Regulation of the immune system Regulation and control of the immune responses by antigen and antibody concentrations, density and types of cytokine receptors; regulation by immune cell circuits and idiotypic regulation; interrelationship between the endocrine, nervous and immune systems. Antibodies and T-cell receptor (TCR) Structure of antibody and TCR, generation of diversity, antigen recognition, processing and presentation. Vaccination Antigens used as vaccines, effectiveness and safety of vaccine, currently used vaccines, adjuvants and passive immunization; possibilities in vaccination against tumor; latest development of vaccines. -- 1 of 3 -- Failure of the immune system Tolerance and autoimmunity, primary and secondary immunodeficiencies, and hypersensitivity. Others Tumor Immunology, Transplantation

目标

1. To provide a basic understanding of the principles of immunology, division of labor and cooperation of the various body cell types in bringing about defense of the body with emphasis on various control mechanisms of the immune system combating infection and disease. 2. To understand various diagnostic and research techniques in immunological research.

先修要求

ABCT2101 Biochemistry and ABCT2102 Molecular Biology

Teaching Pattern

Methodology Lectures are designed to foster understanding of concepts and principles of immunology, improve the student's ability to reason scientifically, and promote understanding of the roles of various components of the immune system and to appreciate the importance of the immune system in combating infection and disease. An active classroom approach is reinforced by teaching aids such as the personal response system. Multimedia means will be used to facilitate conceptual learning. Besides addressing intended learning outcome (a), through the active participation of students and peer-teaching, intended learning outcome (b) that knowledge on the various mechanisms that the body possesses in fighting against pathogens will be reinforced. Students will also be able to predict harmful effects on the body when any of these mechanisms are not working properly including harmful effects of autoimmunity, immunodeficiency, and hypersensitivity. Tutorials are organized to reinforce gasping of concepts and gauzing the progress of students. To address intended learning outcome (c), laboratory practical sessions will be organized and students will be encouraged to develop a thorough understanding of various scientific methods and modern approaches of immunological techniques in the new world that are important for the biotechnology industry, biomedical research as well as from the public health perspectives. Through data analysis and interpretation of the data from laboratory practical sessions, intended learning outcome (d) will also be addressed. Moreover, students will be encouraged to develop a critical approach to problem solving, data handling, and graphics.